The 49ers also are without two wide receivers for the regular-season finale, with wide receiver and return man Ted Ginn Jr. sidelined by an ankle injury and Kyle Williams out with a concussion. Neither practiced all week. Brett Swain starts for Ginn. Wide receiver Joe Hastings was promoted from the practice squad.
Backup A.J. Feeley misses his fourth in a row with a broken thumb on his throwing hand, leaving journeyman Kellen Clemens to make his third consecutive start.
The Associated Press contributed to this report.