Barkley was listed as questionable on New York's final injury report after his third limited practice of the week.
Coach Joe Judge indicated earlier Friday it was looking good for the running back for Week 1. Judge added Barkley has "one more hurdle" to clear today, per Ralph Vacchiano of SNY. As long as Barkley didn't suffer a setback in Friday's practice, he'd be cleared to play.
After practice, Barkley told reporters he didn't suffer a setback, but didn't let on whether he would play Sunday.
"I'ma go in there, I'ma sit down and I'ma say, 'I'ma do whatever the team wants me to do,'" Barkley said. "Whatever they believe is the best thing for me and for the team, and if they feel like it's ready for me to go, then I'm ready to go. If they think I should wait it out a little bit, then I'll wait it out a little bit."
The shifty dual-threat running back missed the bulk of the 2020 season after tearing his ACL in Week 2. The Giants and Barkley played it cautiously throughout the offseason, treading lightly on declaring him ready for the 2021 season opener.
Recent weeks, however, brought optimism that the star back would be able to play against the Broncos.
With no setback today and the RB's questionable designation, it's highly likely Barkley will be on the field Sunday. The Giants could still ease him back in, limiting his reps in the first week depending on how he feels come game day.