Chiefs left tackle Josh Simmons is questionable (illness) minutes before 'MNF' | 'NFL GameDay Kickoff'

NFL Network reporter Cameron Wolfe shares that Kansas City Chiefs offensive tackle may not play against Jacksonville Jaguars on "Monday Night Football".

Kansas City Chiefs defensive end Chris Jones talks to the media about loss to Jacksonville Jaguars.

Kansas City Chiefs quarterback Patrick Mahomes reacts to the 31-28 loss to the Jacksonville Jaguars, saying the team needs to clean things up going forward after committing too many penalties and playing sloppy football.

Jacksonville Jaguars quarterback Trevor Lawrence talks about the Jacksonville Jaguars big Week 5 win vs. the Kansas City Chiefs

Jacksonville Jaguars head coach Liam Coen speaks to the media after the Jags' 31-28 win over the Kansas City Chiefs, praising quarterback Trevor Lawrence's clutch performance and "unbelievable individual effort".

Kansas City Chiefs head coach Andy Reid reflects on the Week 5 loss vs. the Jacksonville Jaguars.

Jacksonville Jaguars rookie phenom Travis Hunter talks about the team's exciting comeback victory against the Kansas City Chiefs in Week 5.

On "NFL GameDay Kickoff", NFL Insider Ian Rapoport gives an update on Baltimore Ravens quarterback Lamar Jackson's hamstring injury and his status for their Week 6 matchup against the Los Angeles Rams.

NFL Network reporter Cameron Wolfe discusses Jacksonville Jaguars offensive plan heading into "Monday Night Football" matchup against the Kansas City Chiefs in Week 6.

NFL media insider Ian Rapoport discusses Los Angeles Chargers running back Omarion Hampton's ankle injury.

NFL media insider Ian Rapoport shares Cincinnati Bengals head coach Zac Taylor's plan to evaluate the quarterback room after loss to Detroit Lions.

NFL Network analyst Kurt Warner discusses the Chiefs offense ahead of Week 5 matchup against the Jacksonville Jaguars on "NFL GameDay Kickoff".

NFL Network's Maurice Jones-Drew offers his ranking of the five best teams in the NFC following Sunday's games in Week 5 of the 2025 season.

Buffalo Bills head coach Sean McDermott shares his takeaways from the Week 5 loss vs. the New England Patriots.

Buffalo Bills quarterback Josh Allen addresses the media after the Week 5 loss vs. the New England Patriots.

Baltimore Ravens head coach John Harbaugh addresses the media after a loss to the Houston Texans in Week 5 of the 2025 NFL season.

Philadelphia Eagles quarterback Jalen Hurts addresses the media after a loss to the Denver Broncos in Week 5 of the 2025 NFL season.

Cleveland Browns defensive end Myles Garrett on facing a Minnesota Vikings depleted O-Line.

"NFL GameDay Kickoff" debates who will stay undefeated longer between the Philadelphia Eagles or the Buffalo Bills.

"NFL GameDay Kickoff" break down will the Baltimore Ravens make playoffs after slow start.

NFL Network Insider Mike Garafolo reporting teams have called the Philadelphia Eagles about potential wide receiver A.J. Brown trade.

San Francisco 49ers QB Mac Jones credits the team's resiliency & toughness after a huge victory over the Los Angeles Rams in Week 5.

Los Angeles Rams wide receiver Davante Adams talks disappointing loss against San Francisco 49ers.

Los Angeles Rams quarterback Matthew Stafford addresses the media after a loss in OT against the San Francisco 49ers in Week 5 of the 2025 season.

Los Angeles Rams running back Kyren Williams discusses performance in overtime loss against the San Francisco 49ers.