Mahomes' fourth TD run of 2025 gives Chiefs a 12-10 lead vs. Lions

Kansas City Chiefs quarterback Patrick Mahomes scrambles into the endzone for a 1-yard touchdown.

Highlights from the Week 6 matchup between the Detroit Lions and the Kansas City Chiefs during the 2025 season.

Watch the best plays from Kansas City Chiefs quarterback Patrick Mahomes game against the Detroit Lions in Week 6 of the 2025 NFL season.

Kansas City Chiefs kicker Harrison Butker knocks in a 33-yard field goal.

Kansas City Chiefs running back Kareem Hunt trucks a Detroit Lion for a 10-yard rush.

Kansas City Chiefs wide receiver Nikko Remigio utilizes the width of the field for a 20-yard punt return.

Kansas City Chiefs quarterback Patrick Mahomes finds wide receiver Marquise Brown in the endzone for a 3-yard touchdown for the second time in "Sunday Night Football" against the Detroit Lions.

Detroit Lions tight end Sam LaPorta corrals a one-handed touchdown pass from quarterback Jared Goff in suffocating pass defense.

Detroit Lions quarterback Jared Goff lobs a short pass to running back David Montgomery for a 23-yard gain.

Kansas City Chiefs tight end Travis Kelce reels in a bobbled ball from quarterback Patrick Mahomes for a 17-yard gain.

Kansas City Chiefs wide receiver Marquise Brown grabs a short toss from quarterback Patrick Mahomes for a 9-yard touchdown.

Kansas City Chiefs tight end Noah Gray corrals a short pass from Patrick Mahomes for a 19-yard catch and run.

Kansas City Chiefs wide receiver Marquise Brown snags a 13-yard pass from quarterback Patrick Mahomes with a tippy toe finish.

Kansas City Chiefs tight end Travis Kelce is flipped over a Detroit Lion following a 17-yard pass from quarterback Patrick Mahomes.

Detroit Lions running back Jahmyr Gibbs finds a hole in the Kansas City Chiefs defense for a 15-yard rush.

Detroit Lions tight end Sam LaPorta is open in midfield for a 26-yard dot from quarterback Jared Goff.

Kansas City Chiefs quarterback Patrick Mahomes spins out of a sack and finds wide receiver Marquise Brown for a 20-yard gain.

Detroit Lions quarterback Jared Goff locates wide receiver Jameson Williams for a 22-yard touchdown.

Detroit Lions tight end Sam LaPorta reels in a short pass from quarterback Jared Goff for an 11-yard gain.

Kansas City Chiefs kicker Harrison Butker misses the extra-point attempt.

Kansas City Chiefs wide receiver Xavier Worthy corrals a 6-yard touchdown pass from quarterback Patrick Mahomes.

Kansas City Chiefs quarterback Patrick Mahomes finds wide receiver JuJu Smith-Schuster for a 30-yard catch and run.

Detroit Lions kicker Jake Bates nails a 28-yard field goal.

Kansas City Chiefs tight end Travis Kelce barrels through Detroit Lions defenders for a 15-yard gain off a pass from quarterback Patrick Mahomes.

Detroit Lions quarterback Jared Goff gets tricky with a receiving touchdown from running back David Montgomery, but the call is reversed due to a penalty on Goff.