Fuller is officially inactive and will not play in the wild-card game due to the lingering groin injury.
Fuller, who was listed as questionable on the injury report, was considered a game-time decision by the Texans. NFL Network's James Palmer noted earlier this week that Fuller was a long shot to play after he was limited in practice this week.
The fourth-year receiver suffered the injury 18 snaps into Week 16's win. Fuller, who also missed the regular-season finale, had a chance to return for Wild Card Weekend, per Rapoport.
When healthy, Fuller's presence boosts the Texans' offense, and is a downfield threat, but is oft injury prone.
In 11 games this season, Fuller tallied 670 yards on 49 receptions with three touchdowns.