Arizona Cardinals running back James Conner, who played his college ball at Pitt and his first four NFL seasons in the same stadium with the Steelers, grinded down the Black and Gold for 105 yards and two touchdowns during his first game back in Pittsburgh.

Mike Tomlin's familiarity with just how good James Conner is stands as the foremost reason he doesn't want Conner to have a happy homecoming Sunday when the Arizona Cardinals face the host Pittsburgh Steelers.

The Cardinals are activating RB James Conner (knee) off injured reserve ahead of their Week 10 matchup versus the Atlanta Falcons, NFL Network Insider Ian Rapoport reported.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

Cardinals running back James Conner is being placed on injured reserve due to a knee injury, NFL Network Insiders Ian Rapoport and Tom Pelissero reported. Conner suffered the injury in Arizona's Week 5 loss to the Bengals.

Here are the injuries and news we're monitoring around the league on this Week 5 Sunday.

In today's NFL, running backs have a multitude of responsibilities. So, who are the truly well-rounded stars at the position? After crunching the numbers, the Next Gen Stats analytics team provides the top 10 most complete RBs. Where does rookie sensation Bijan Robinson rank?

Is De'Von Achane a must-start player? What to do with Rhamondre Stevenson in a tough matchup? Check out all of Michael F. Florio's RB starts and sits for Week 5 of the NFL fantasy football season.

Maurice Jones-Drew reveals his ranking of the NFL's top 15 running backs at the quarter mark of the 2023 season. How many rookies make his list? Which team has two representatives?

Maurice Jones-Drew revisits his preseason rankings of all 32 RB1s and promises to stop underestimating one veteran rusher. Plus, he updates his top 15 RBs heading into Week 4.

Nine NFL teams remain winless in the 2023 season. Who has the most hope to turn things around before it's too late? Kevin Patra provides his rankings.

After failing to reach 50 yards rushing in either of the first two weeks, Najee Harris could be poised for a big game on Sunday night. Check out all of Michael F. Florio's RB starts and sits for Week 3 of the NFL fantasy football season.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

The NFL fantasy team takes a crack at making bold predictions for the 2023 fantasy season. Who will be this season's top scorer? Which ascending player will claim his spot atop the WR throne?

Maurice Jones-Drew ranks all 32 RB1s heading into the 2023 NFL season. Is Saquon Barkley too low after a major bounce-back campaign? And who earns the No. 1 spot? Check out MJD's full pecking order.

Dak Prescott is coming off an underwhelming season. Is now the perfect time to scoop up one of the more reliable fantasy QBs of recent years? Michelle Magdziuk identifies the seven safest players available in the middle rounds of drafts in 2023. 

The 2023 NFL fantasy football season is here! Fantasy guru Adam Rank is here to help you prepare for your drafts by revealing his running back rankings and tiers.

Seven teams are still searching for their first player to win Most Valuable Player heading into 2023. Who from the Cardinals, Texans, Jaguars, Saints, Jets, Eagles and Buccaneers is most likely to bring home the award?

Facing an uphill climb to contention after a 4-13 season, Cardinals running back James Conner finds it exciting that nobody seems to believe in Arizona.

Maurice Jones-Drew assembles the perfect running back, combining the traits of some of today's top talent in the NFL. Who has the best hands? Ideal size? Top speed?

Maurice Jones-Drew evaluated every running back who started a game during the 2022 NFL regular season to create a COMPLETE ranking, from 1 to 75. Did rushing champion Josh Jacobs finish on top?

Maurice Jones-Drew ranks each team's primary starting running back for the 2022 NFL season. Which player earns the No. 1 spot?

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

Joel Smyth assembles the best DFS lineup for you in Week 17 of the 2022 NFL season.

NFL Network's Kyle Brandt crowns Week 13 angry runs winner.

"GMFB" awards Sunday Week 13 game ball.

Watch Arizona Cardinals running back James Conner's best runs from 2-TD game vs. his former team, the Pittsburgh Steelers, during Week 13 of the 2023 NFL season.

Arizona Cardinals running back James Conner rumbles forward for 11-yard rush to cap Cards' victory vs. Pittsburgh Steelers.

Arizona Cardinals running back James Conner cuts it inside for 29-yard rush late in fourth quarter to set up Cards' near midfield.

Arizona Cardinals running back James Conner's second TD vs. his former team extends Cards' lead to 23-3 midway through fourth quarter.

Arizona Cardinals running back James Conner's 1-yard TD run vs. Pittsburgh Steelers extends Cards' lead to 16-3 midway through third quarter, capitalizing on the turnover.

Arizona Cardinals running back James Conner sends Pittsburgh Steelers cornerback Patrick Peterson flying with lethal stiff-arm during penalty-negated play.

Pittsburgh Steelers head coach Mike Tomlin on Arizona Cardinals running back James Conner.

Watch a countdown of the 10 best highlight plays made by the Arizona Cardinals through the first nine weeks of the 2023 regular season.

Arizona Cardinals running back James Conner (knee) was placed on injured reserve.

Arizona Cardinals running back James Conner breaks loose for 35-yard run vs. the Cincinnati Bengals.

NFL Network's Adam Rank, Cynthia Frelund and Kimmi Chex explain why they're trying to part ways with these three players in fantasy football right now: Arizona Cardinals running back James Conner, Miami Dolphins RB De'Von Achane and Houston Texans RB Dameon Pierce.

NFL Network's Cynthia Frelund reveals whether or not Arizona Cardinals running back James Conner will exceed the 15-point mark in fantasy football during Week 4 of the 2023 season, when he faces the San Francisco 49ers defense.

Watch the top runs during Week 3 of the 2023 NFL season.

Arizona Cardinals running back James Conner's best plays vs. Dallas Cowboys | Week 3

Watch highlights from the Week 3 matchup between the Dallas Cowboys and the Arizona Cardinals.

Arizona Cardinals running back James Conner bursts off the left side for a 26-yard pickup.

Arizona Cardinals running back James Conner wins pylon race for 5-yard touchdown rush.

Arizona Cardinals running back James Conner bursts through the left side of the line for a 20-yard gain.

NFL Network's Michael F. Florio reveals why he's benching Arizona Cardinals running back James Conner in Week 3 vs. the Dallas Cowboys.

NFL Network's Cynthia Frelund, Patrick Claybon and Adam Rank go into detail about the fantasy football performances put forth by Tampa Bay Buccaneers QB Baker Mayfield, WR Mike Evans, Dallas Cowboys WR CeeDee Lamb and Arizona Cardinals RB James Conner in Week 2 of the 2023 season.

Watch Arizona Cardinals running back James Conner's best runs in his 106-yard game vs. the New York Giants in Week 2 of the 2023 NFL season.

Arizona Cardinals running back James Conner amps up Arizona crowd by slamming turf after 9-yard run.

Arizona Cardinals running back James Conner infiltrates Giants' secondary for 22-yard rush as the Cardinals have the perfect play to counter the Giants' blitz.