NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

It's only early June, but the injury bug has already arrived in Santa Clara. Two 49ers, offensive lineman Justin Skule and defensive back Tarvarius Moore, suffered significant injuries during Monday's OTAs session.

Chris Wesseling assesses the landscape of NFL offenses now that the draft has concluded and the majority of free-agent signings are in the books. Which units are the most potent? Here are the top 10 attacks heading into the 2020 season.

After days of speculation, it has been confirmed: San Francisco 49ers tight end George Kittle will not suit up on "Monday Night Football." He was listed as doubtful with a knee/ankle injury on Saturday.

The San Francisco 49ers look to welcome back LT Joe Staley and FB Kyle Juszczyk on Monday night as they look to widen their lead in the NFC West and remain the only undefeated team in the NFL.

After losing fullback Kyle Juszczyk for up to six weeks with an MCL sprain, San Francisco learned this week that it will be without its starting right tackle for a similar amount of time.

Quarterbacks Baker Mayfield and Jimmy Garoppolo will square off for the first time ever when the San Francisco 49ers and Cleveland Browns clash on "Monday Night Football" to close Week 5.

San Francisco 49ers general manager John Lynch said No. 2 overall pick Nick Bosa has a "50-50" chance of returning for the 49ers' season opener.