Brandon Aiyuk

Brandon Aiyuk going without a target in Week 1 left 49ers fans concerned the former first-round pick may be falling out of favor in San Francisco. HC Kyle Shanahan said Aiyuk's participation rate was a product of an inconsistent training camp due to injury and an impressive preseason from Trent Sherfield.

You have lineup questions. We have answers. At least we hope. Start 'Em, Sit 'Em is back for the 2021 NFL season.

With Deebo Samuel figuring to take the lion's share and Trent Sherfield emerging, second-year 49ers wideout Brandon Aiyuk could see his targets take a dip if he doesn't step up and stand out.

You have lineup questions. We have answers. At least we hope. Start 'Em, Sit 'Em is back for the 2021 NFL season.

What's the latest on the health of Saquon Barkley, Dak Prescott and Odell Beckham Jr.? Could the Colts turn to a rookie quarterback to fill in for Carson Wentz? Gregg Rosenthal takes a look at the juiciest tidbits escaping from training camps across the NFL.

Is Bears WR Darnell Mooney about establish himself as a preeminent deep threat? Will Daniel Jones flourish with the Giants' upgraded weaponry? Can Trevon Diggs lock down one side of the field for the Cowboys? Gregg Rosenthal spotlights one Making the Leap candidate for each NFC team.

Is Jalen Hurts set to break through in Year 2? Could David Montgomery soar to new heights in Chicago? Marc Sessler has identified one prime candidate from each NFC team to earn a first Pro Bowl nod in 2021.

After an injury-riddled 2020 season, the San Francisco 49ers are back with a roster that appears loaded on paper. Can Kyle Shanahan get them back to the Super Bowl? Adam Rank examines the state of the franchise ahead of the 2021 campaign.

Since divisional realignment back in 2002, we've only experienced two NFL seasons in which at least one team didn't go from worst to first. Who could accomplish the feat in 2021? Adam Schein ranks the eight candidates.

Jeffri Chadiha spotlights five teams that should be doing whatever they can to give Falcons star Julio Jones the fresh start he's looking for, including Bill Belichick's Patriots.

Which roster looks best in the NFL's toughest division? Is the Rams' top-heavy blueprint built for success? Can the 49ers return to the Super Bowl with a rookie at quarterback? Gregg Rosenthal projects the starters for every team in the NFC West.

Did the 49ers take advantage of having two first-round picks in the 2020 NFL Draft? Should the Cardinals regret taking hybrid defender Isaiah Simmons over an offensive tackle? Gennaro Filice grades the rookie class of each NFC West team.

Washington and Cleveland just turned putrid seasons from 2019 into playoff journeys in 2020. Which NFL teams could follow suit in the 2021 campaign? Marc Sessler spotlights four particular franchises.

With the 2020 NFL regular season in the books, Daniel Jeremiah provides a final ranking of the top 25 rookies. Who's No. 1: Justin Herbert, Justin Jefferson or Chase Young?

With two games left in the regular season, David Carr selects his Offensive All-Rookie Team. Who makes the list? Who's left off? Plus, he updates his top-15 offensive player rankings ahead of Week 16.

Adam Rank breaks down which wide receivers you should start and which ones you should sit for Week 15 of the 2020 NFL fantasy football season.

Justin Herbert overtakes Joe Burrow for the top spot in Daniel Jeremiah's ranking of the 25 best rookies through Week 9 of the 2020 season.

Kyle Shanahan's 49ers are in the midst of a season in which they're encountering incredibly unfortunate amounts of injuries, but he's not pointing to the two reserve lists -- injured and COVID-19 -- with fingers of blame.

San Francisco 49ers wide receivers Brandon Aiyuk and Deebo Samuel and offensive tackle Trent Williams are being placed on the reserve/COVID-19 list and will be out for Thursday night's game against the Green Bay Packers, which is still on as scheduled, NFL Network's Mike Garafolo reported Wednesday night. 

After missing Week 1 due to a hamstring injury, Brandon Aiyuk has progressively become more involved in the 49ers offense and is coming off back-to-back big games. 

Every week this article will look at the best and toughest matchups for each position in fantasy football. It also will give you five players whose fantasy value is on the rise.

Adam Rank breaks down which wide receivers you should start and which ones you should sit for Week 8 of the 2020 NFL fantasy football season.

Marcas Grant breaks down his picks for players worth a look on the fantasy waiver wire following Week 7.

Joe Burrow leads the field and an undrafted sensation cracks the top 10 in Daniel Jeremiah's ranking of the 25 best rookies through Week 4 of the 2020 season.

Marcas Grant breaks down his picks for players worth a look on the fantasy waiver wire following Week 4.

San Francisco 49ers wide receiver Brandon Aiyuk makes a one-handed reception over the defender for 26 yards.

Watch the San Francisco 49ers best plays from the first four weeks of the 2021 season.

NFL analyst Brian Baldinger breaks down how San Francisco 49ers quarterback Jimmy Garoppolo set up his team for success in Week 3 despite their loss to the Green Bay Packers.

Watch all of the highlights from the Green Bay Packers and San Francisco 49ers from their Week 3 matchup on "Sunday Night Football" in the 2021 NFL regular season.

San Francisco 49ers wide receiver Brandon Aiyuk's filthy route leads to his first touchdown of 2021.

NFL players share their favorite Nickelodeon shows.

NFL Network's Adam Rank's fantasy starts and sits for Week 1.

NFL Network's Patrick Claybon, Cynthia Frelund, Adam Rank and Michael F. Florio share their top flex players to start in fantasy football in Week 1.

NFL Network's Patrick Claybon, Marcas Grant, Michael F. Florio and Adam Rank highlight their must-have players to draft in fantasy football in 2021.

NFL Network's Patrick Claybon, Marcas Grant, Kimmi Chex and Adam Rank highlight their favorite mid-round fantasy football draft gems for 2021.

NFL Network's Mike Yam catches up with San Francisco 49ers wide receiver Brandon Aiyuk to talk about his comfort level entering Year 2, his relationship with WR Deebo Samuel and his team's quarterback situation.

Marcas Grant counts down his top 5 fantasy football breakout players for the 2021 NFL season.

Marcas Grant counts down his top 10 breakout players for the 2021 fantasy football season. Find out which second-year quarterback he says could lead you to a fantasy championship in 2021. Plus, see which two rookies make the cut, and why a surprise running back claims the top spot on Grant's list.

The "Good Morning Football" crew highlights second-year WRs poised for breakout 2021 seasons.

Relive the top moments from every team's top wide receiver play from the 2020 NFL season.

Watch the best plays by the San Francisco 49ers from the 2020 NFL season.

Watch the highlights of San Francisco 49ers wide receiver Brandon Aiyuk from the 2020 NFL season.

Watch the top rookie plays during the NFL 2020 season.

Watch the top trick plays that happened in the 2020 NFL season.

Here are the top 10 scoring rookies from the 2020 NFL season, led by 299.8 from Saints QB Justin Herbert.

Watch all the highlights of the Week 16 matchup between the San Francisco 49ers and the Arizona Cardinals.

San Francisco 49ers quarterback C.J. Beathard's lead block helps spring wide receiver Brandon Aiyuk's 16-yard run against the Arizona Cardinals.

Watch the top catches of Week 15 during the NFL 2020 season.

Watch highlights from the Week 15 matchup between the San Francisco 49ers and the Dallas Cowboys.

San Francisco 49ers cook up trickery with wide receiver Brandon Aiyuk touchdown on fourth-and-goal.