All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em for your 2022 NFL fantasy football league.

The 2022 NFL fantasy football season is just around the corner! Marcas Grant breaks down 12 players who are being drafted too low.

Niners wide receiver Brandon Aiyuk generated 748 yards and five touchdowns as a rookie. The expectations in San Francisco suggest he could blast past those numbers this season.

In response to Niners players exchanging punches -- most notably linebacker Fred Warner and wide receiver Brandon Aiyuk -- at Tuesday's practice, Shanahan let it be known Friday that he wants his players to be tough, to be physical, to even be "irritants," but he doesn't want them throwing hands.

With 32 separate 53-man rosters across the NFL, it's easy for key contributors to fly under the radar. Today, Nick Shook spotlights one unsung hero from each NFC team.

NFL.com's Chase Goodbread breaks down four things to watch for when the San Francisco 49ers visit the Tennessee Titans in a TNF matchup full of playoff implications.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

Michael F. Florio breaks down the top fantasy football matchups for Week 14 of the 2021 NFL season.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

Will Patrick Mahomes' Chiefs or Micah Parsons' Cowboys stand tall as the playoff race takes shape over the final month of the 2021 NFL season? Can Justin Herbert handle a big upcoming test? Jeffri Chadiha digs into that and more ahead of Week 15.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

Michael F. Florio breaks down the top fantasy football matchups for Week 12 of the 2021 NFL season.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

Michael F. Florio breaks down which players you should target on the waiver wire ahead of Week 10 of the 2021 NFL Fantasy Football season.

Michael F. Florio breaks down which players you should target on the waiver wire ahead of Week 9 of the 2021 NFL Fantasy Football season.

Michael F. Florio breaks down which players you should target on the waiver wire ahead of Week 8 of the 2021 NFL Fantasy Football season.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

Brandon Aiyuk going without a target in Week 1 left 49ers fans concerned the former first-round pick may be falling out of favor in San Francisco. HC Kyle Shanahan said Aiyuk's participation rate was a product of an inconsistent training camp due to injury and an impressive preseason from Trent Sherfield.

You have lineup questions. We have answers. At least we hope. Start 'Em, Sit 'Em is back for the 2021 NFL season.

With Deebo Samuel figuring to take the lion's share and Trent Sherfield emerging, second-year 49ers wideout Brandon Aiyuk could see his targets take a dip if he doesn't step up and stand out.

You have lineup questions. We have answers. At least we hope. Start 'Em, Sit 'Em is back for the 2021 NFL season.

What's the latest on the health of Saquon Barkley, Dak Prescott and Odell Beckham Jr.? Could the Colts turn to a rookie quarterback to fill in for Carson Wentz? Gregg Rosenthal takes a look at the juiciest tidbits escaping from training camps across the NFL.

Is Bears WR Darnell Mooney about establish himself as a preeminent deep threat? Will Daniel Jones flourish with the Giants' upgraded weaponry? Can Trevon Diggs lock down one side of the field for the Cowboys? Gregg Rosenthal spotlights one Making the Leap candidate for each NFC team.

Is Jalen Hurts set to break through in Year 2? Could David Montgomery soar to new heights in Chicago? Marc Sessler has identified one prime candidate from each NFC team to earn a first Pro Bowl nod in 2021.

After an injury-riddled 2020 season, the San Francisco 49ers are back with a roster that appears loaded on paper. Can Kyle Shanahan get them back to the Super Bowl? Adam Rank examines the state of the franchise ahead of the 2021 campaign.

San Francisco 49ers quarterback Jimmy Garoppolo dots 49ers wide receiver Brandon Aiyuk over the middle for a 20-yard gain.

San Francisco 49ers quarterback Jimmy Garoppolo locates 49ers wide receiver Brandon Aiyuk in the end zone for a 3-yard touchdown

NFL analyst Brian Baldinger breaks down San Francisco 49ers quarterback Jimmy Garoppolo's performance in Week 2 of the 2022 NFL season.

San Francisco 49ers quarterback Jimmy Garoppolo fires a 14-yard pass to wide receiver Brandon Aiyuk.

San Francisco 49ers quarter back Trey Lance completes a 31-yard pass to wide receiver Brandon Aiyuk against the Chicago Bears.

NFL Network's Michael F. Florio, Marcas Grant, and Adam Rank discuss whether Denver Broncos quarterback Russell Wilson, San Francisco 49ers wide receiver Brandon Aiyuk, Kansas City Chiefs running back Clyde Edwards-Helaire, and Las Vegas Raiders tight end Darren Waller deserve second chances going into the 2022 NFL season after disappointing fantasy numbers last year.

NFL Network's Peter Schrager reveals players No. 7, 8 on "breakout players" of '22 season.

San Francisco 49ers wide receiver Brandon Aiyuk discusses the 'tempers flaring' moment at practice between him and 49ers linebacker Fred Warner.

See what changes the San Francisco 49ers made to their roster this past off-season along with predictions on their best and worst case scenarios.

NFL writer Nick Shook gives us his unsung players on each team for the 2021 season.

NFL Network's Nick Shook names the players who stood out as unsung heroes of the 2021 NFL season.

Watch the 10 best highlight plays made by the San Francisco 49ers in the 2021 NFL season.

The top 3 longest throws by air distance from the Conference Championship round of the 2021 NFL postseason, according to Next Gen Stats.

San Francisco 49ers quarterback Jimmy Garoppolo lofts a 31-yard sideline rainbow to wide receiver Brandon Aiyuk.

Watch the Top 5 fastest ball carriers from Super Wild Card Weekend, according to Next Gen Stats.

Dallas Cowboys cornerback Trevon Diggs loses track of San Francisco 49ers wide receiver Brandon Aiyuk on WR's 37-yard catch and run.

San Francisco 49ers wide receiver Brandon Aiyuk's Herculean reach for first-down marker merits attention.

Which NFC players could be true wild cards this weekend? NFL Network's David Carr, LaDainian Tomlinson weigh in.

San Francisco 49ers wide receiver Brandon Aiyuk settles in an open sideline window for a 31-yard catch and run.

San Francisco 49ers wide receiver Brandon Aiyuk's 25-yard catch and run gives the 49ers a shot at a field goal to end the half.

San Francisco 49ers wide receiver Brandon Aiyuk snags a contested grab on 49ers quarterback Jimmy Garoppolo's 19-yard strike in stride.

NFL analyst Brian Baldinger breaks down San Francisco 49ers QB Trey Lance's performance in the Week 17 win over the Houston Texans.

San Francisco 49ers wide receiver Brandon Aiyuk breaks through the Houston Texans defense for a 43-yard gain.

San Francisco 49ers wide receiver Brandon Aiyuk shows off his toe-drag swag against the Houston Texans.

San Francisco 49ers quarterback Jimmy Garoppolo caps a game-tying 95-yard drive with a touchdown to wide receiver Brandon Aiyuk.